CRPC treatment

Revolutionizing Castration-Resistant Prostate Cancer (CRPC) Treatment: Radium-223 Dichloride at Anadolu Medical Center

What You Learn In This Article:

When it comes to managing castration-resistant prostate cancer (CRPC) patients with symptomatic bone metastases, Anadolu Medical Center is leading the way with a groundbreaking treatment. This novel approach involves the use of targeted radiopharmaceutical therapy, approved by the FDA, to bring new hope to those facing this challenging condition.

Targeted Radiopharmaceutical Therapy: A Game-Changer for CRPC

The treatment in question harnesses the power of radioactive isotopes that are designed to zero in on and deliver precise radiation to cancer cells in the bones. One such radiopharmaceutical therapy, known as radium-223 dichloride (marketed under the brand name Xofigo), has emerged as a beacon of promise in the fight against CRPC.

How Radium-223 Works

Radium-223 is an alpha-emitting radioactive isotope that cleverly mimics the behavior of calcium. This mimicry allows it to selectively target areas of heightened bone turnover, particularly those affected by bone metastases. Once inside the bone, radium-223 releases high-energy alpha particles, leading to localized damage in the DNA of cancer cells. This targeted attack ultimately results in cell death, offering newfound optimism to CRPC patients.

Clinical Success and Benefits

Clinical trials have unveiled the true potential of radium-223. It not only improves overall survival but also significantly delays the onset of skeletal-related events such as fractures or spinal cord compression in CRPC patients with symptomatic bone metastases. This therapy is often recommended for patients who have either exhausted other systemic treatments, like chemotherapy or androgen receptor-targeted agents or are ineligible for them.

Convenient Administration

Radium-223 therapy is administered through a simple intravenous injection every four weeks for a total of six doses. While it comes with some common side effects such as low blood cell counts (anemia, neutropenia, and thrombocytopenia) and gastrointestinal symptoms like nausea, diarrhea, and vomiting, these effects are usually manageable and temporary.

Experience the Difference at Anadolu Medical Center

In collaboration with the prestigious Mayo Clinic, Anadolu Medical Center is at the forefront of CRPC treatment. Patients can trust our world-class facilities and the expertise of their medical team to deliver this cutting-edge therapy.

The combination of FDA approval, successful experiences with referred patients, and the expertise of Anadolu Medical Center and the Mayo Clinic make radium-223 dichloride a beacon of hope for CRPC patients. Experience a new era of treatment at Anadolu Medical Center.


Dr. Soheil Najafi Mehri

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